Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (1997))
Withdrawn drug?	Yes

IUPAC Name

1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine

International Nonproprietary Names
INN number	INN
6124	sibutramine

Synonyms

Meridia® | sibutramine hydrochloride

Comments

Use of sibutramine is reported to increase risk of heart attack and stroke in patients with a history of heart disease. For this reason sibutramine has been withdrawn from use in some countries.

Database Links
CAS Registry No.	106650-56-0 (source: Scifinder)
ChEBI	CHEBI:458192
ChEMBL Ligand	CHEMBL1419
DrugBank Ligand	DB01105
GtoPdb PubChem SID	135651043
PubChem CID	5210
Search Google for chemical match using the InChIKey	UNAANXDKBXWMLN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	UNAANXDKBXWMLN
Search PubMed clinical trials	sibutramine
Search PubMed titles	sibutramine
Search PubMed titles/abstracts	sibutramine
Search UniChem for chemical match using the InChIKey	UNAANXDKBXWMLN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	UNAANXDKBXWMLN
Wikipedia	Sibutramine