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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1997)) |
Withdrawn drug? | Yes |
IUPAC Name ![]() |
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine |
International Nonproprietary Names ![]() |
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INN number | INN |
6124 | sibutramine |
Synonyms ![]() |
Meridia® | sibutramine hydrochloride |
Comments |
Use of sibutramine is reported to increase risk of heart attack and stroke in patients with a history of heart disease. For this reason sibutramine has been withdrawn from use in some countries. |
Database Links ![]() |
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CAS Registry No. | 106650-56-0 (source: Scifinder) |
ChEBI | CHEBI:458192 |
ChEMBL Ligand | CHEMBL1419 |
DrugBank Ligand | DB01105 |
GtoPdb PubChem SID | 135651043 |
PubChem CID | 5210 |
Search Google for chemical match using the InChIKey | UNAANXDKBXWMLN-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | UNAANXDKBXWMLN |
Search PubMed clinical trials | sibutramine |
Search PubMed titles | sibutramine |
Search PubMed titles/abstracts | sibutramine |
Search UniChem for chemical match using the InChIKey | UNAANXDKBXWMLN-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | UNAANXDKBXWMLN |
Wikipedia | Sibutramine |