triiodothyronine

Ligand Id: 2634
Ligand name triiodothyronine
Abbreviated name T3

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 650.79
XLogP 2.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1956))
IUPAC Name
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
International Nonproprietary Names
INN number INN
653 liothyronine
Synonyms
3,5,3'-triodo-L-thyronine
Cytomel®
liothyronine sodium
Database Links
BindingDB Ligand 18860
CAS Registry No. 6893-02-3 (source: ChEBI)
ChEBI CHEBI:18258
ChEMBL Ligand CHEMBL1544
DrugBank Ligand DB00279
Human Metabolome Database HMDB00265
NURSA Ligand 10.1621/1QGKELTJ7R
PharmGKB Drug PA164778866
PubChem CID 5920
RCSB PDB Ligand T3
Search Google for chemical match using the InChIKey AUYYCJSJGJYCDS-LBPRGKRZSA-N
Search Google for chemicals with the same backbone AUYYCJSJGJYCDS
Search PubMed clinical trials liothyronine
Search PubMed titles liothyronine
Search PubMed titles/abstracts liothyronine
Wikipedia Liothyronine
Comments
Thyroid hormone receptor agonist