T3

Ligand Id: 2634
Ligand name T3

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 650.79
XLogP 2.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1956))
DrugBank groups Approved
IUPAC Name
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
International Nonproprietary Names
INN number INN
653 liothyronine
Synonyms
3,5,3'-triodo-L-thyronine
T3
thyroid hormone
triiodothyronine
Database Links
BindingDB Ligand 18860
CAS Registry No. 6893-02-3 (source: ChEBI)
ChEBI CHEBI:18258
ChEMBL Ligand CHEMBL1544
DrugBank Ligand DB00279
Human Metabolome Database HMDB00265
NURSA Ligand li48
PharmGKB Drug PA450237, PA164778866
PubChem CID 5920
RCSB PDB Ligand T3
Search Google for chemical match using the InChIKey AUYYCJSJGJYCDS-LBPRGKRZSA-N
Search Google for chemicals with the same backbone AUYYCJSJGJYCDS
Search PubMed clinical trials liothyronine
Search PubMed titles liothyronine
Search PubMed titles/abstracts liothyronine
Wikipedia Liothyronine
ZINC ZINC03830999
Comments
Thyroid hormone receptor agonist