troglitazone

Ligand Id: 2693
Ligand name troglitazone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 110.16
Molecular weight 441.16
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1997))
DrugBank groups withdrawn
IUPAC Name
5-[[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
International Nonproprietary Names
INN number INN
6851 troglitazone
Synonyms
CS-045
Database Links
BindingDB Ligand 50085045
CAS Registry No. 97322-87-7 (source: ChEBI)
ChEBI CHEBI:9753
ChEMBL Ligand CHEMBL408
DrugBank Ligand DB00197
NURSA Ligand 1141
PharmGKB Drug PA451799
PubChem CID 5591
RCSB PDB Ligand TDZ
Search Google for chemical match using the InChIKey GXPHKUHSUJUWKP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GXPHKUHSUJUWKP
Search PubMed clinical trials troglitazone
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Wikipedia Troglitazone
ZINC ZINC00968276
Comments
Troglitazone is an antidiabetic and anti-inflammatory drug.