SR11237

Ligand id: 2809

Name: SR11237

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 55.76
Molecular weight 380.2
XLogP 7.88
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-dioxolan-2-yl]benzoic acid
Synonyms
BMS 649  | SR-11237
Database Links
BindingDB Ligand 50033077
CAS Registry No. 146670-40-8 (source: Scifinder)
ChEMBL Ligand CHEMBL112715
PubChem CID 127019
Search Google for chemical match using the InChIKey ZZUKALQMHNSWTK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZZUKALQMHNSWTK
Search UniChem for chemical match using the InChIKey ZZUKALQMHNSWTK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZZUKALQMHNSWTK
Comments
SR11237 is a pan retinoid X receptor (RXR) agonist that is devoid of any retinoic acid receptor (RAR) activity [2].