zaprinast

Ligand id: 2919

Name: zaprinast

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 62.39
Molecular weight 272.11
XLogP 2.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-(2-propoxyphenyl)-2,3-dihydrotriazolo[4,5-e]pyrimidin-7-one
International Nonproprietary Names
INN number INN
5096 zaprinast
Synonyms
M&B-22948
Database Links
BindingDB Ligand 50020870
CAS Registry No. 37762-06-4 (source: Scifinder)
ChEMBL Ligand CHEMBL28079
PubChem CID 5722
Search Google for chemical match using the InChIKey REZGGXNDEMKIQB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone REZGGXNDEMKIQB
Search PubMed clinical trials zaprinast
Search PubMed titles zaprinast
Search PubMed titles/abstracts zaprinast
Search UniChem for chemical match using the InChIKey REZGGXNDEMKIQB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone REZGGXNDEMKIQB
Wikipedia Zaprinast
Comments
Zaprinast is a phosphodiesterase inhibitor. It failed as a clinical drug candidate.