meglutol

Ligand id: 2960

Name: meglutol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 94.83
Molecular weight 162.05
XLogP -0.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-hydroxy-3-methylpentanedioic acid
International Nonproprietary Names
INN number INN
4448 meglutol
Database Links
CAS Registry No. 503-49-1 (source: Scifinder)
ChEMBL Ligand CHEMBL50444
DrugBank Ligand DB04377
PubChem CID 1662
RCSB PDB Ligand MAH
Search Google for chemical match using the InChIKey NPOAOTPXWNWTSH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NPOAOTPXWNWTSH
Search PubMed clinical trials meglutol
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Search UniChem for chemical match using the InChIKey NPOAOTPXWNWTSH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NPOAOTPXWNWTSH
Wikipedia Meglutol
Comments
Meglutol is a hypolipidemic (lipid-lowering) agent. It is thought to inhibit HMG-CoA reductase and interfere with the conversion of acetate to HMG-CoA [1].