zibotentan

Ligand id: 3539

Name: zibotentan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 141.37
Molecular weight 424.1
XLogP 2.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide
International Nonproprietary Names
INN number INN
8664 zibotentan
Synonyms
ZD 4054 | ZD-4054 | ZD4054
Database Links
CAS Registry No. 186497-07-4 (source: Scifinder)
ChEMBL Ligand CHEMBL1628688
PubChem CID 9910224
Search Google for chemical match using the InChIKey FJHHZXWJVIEFGJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FJHHZXWJVIEFGJ
Search PubMed clinical trials zibotentan
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Search UniChem for chemical match using the InChIKey FJHHZXWJVIEFGJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FJHHZXWJVIEFGJ
Wikipedia Zibotentan
Comments
Zibotentan is an endothelin receptor antagonist. It has been assessed as an anti-cancer treatment. Click here to link to ClinicalTrials.gov's list of zibotentan/ZD4054 trials.