piclidenoson

Ligand id: 422

Name: piclidenoson

Abbreviated name: IB-MECA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 134.42
Molecular weight 510.05
XLogP 1.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S,3S,4R,5R)-3,4-dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyloxolane-2-carboxamide
International Nonproprietary Names
INN number INN
10136 piclidenoson
Synonyms
CF 101 | CF101 | N(6)-ibamu
Database Links
BindingDB Ligand 50118812
CAS Registry No. 152918-18-8 (source: Scifinder)
ChEBI CHEBI:73286
ChEMBL Ligand CHEMBL119709
PubChem CID 123683
Search Google for chemical match using the InChIKey HUJXGQILHAUCCV-MOROJQBDSA-N
Search Google for chemicals with the same backbone HUJXGQILHAUCCV
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Search UniChem for chemical match using the InChIKey HUJXGQILHAUCCV-MOROJQBDSA-N
Search UniChem for chemicals with the same backbone HUJXGQILHAUCCV
Comments
Piclidenoson is a selective agonist of the adenosine A3 receptor. It has anti-inflammatory action which is being investigated for translation to the clinic [2].
Early investigations revealed anti-cancer effects [1,5,12].