S18986

Ligand id: 4304

Name: S18986

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 57.79
Molecular weight 224.06
XLogP 1.34
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(6S)-8$l^{6}-thia-2,7-diazatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-triene-8,8-dione
Synonyms
S 18986 | S-18986
Database Links
CAS Registry No. 175340-20-2 (source: Scifinder)
ChEMBL Ligand CHEMBL320642
PubChem CID 637863
Search Google for chemical match using the InChIKey MNTIJYGEITVWHU-SNVBAGLBSA-N
Search Google for chemicals with the same backbone MNTIJYGEITVWHU
Search UniChem for chemical match using the InChIKey MNTIJYGEITVWHU-SNVBAGLBSA-N
Search UniChem for chemicals with the same backbone MNTIJYGEITVWHU
Wikipedia S-18986
Comments
S18968 is a positive allosteric modulator of AMPA-type glutamate receptors (an AMPA potentiator), with potential cognition-enhancing properties [1-2]. S18986 corresponds to the S enantiomer.