Ligand Id: 4563
Ligand name folic acid

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 7
Rotatable bonds 10
Topological polar surface area 208.66
Molecular weight 442.15
XLogP -2.93
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues
Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: DrugBank)
DrugBank groups approved; nutraceutical
IUPAC Name
(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Summary of Clinical Use
A member of the B vitamin family, used in the treatment of megaloblastic anemia and folate deficiencies. Converted in the liver to dihydrofolic acid.
International Nonproprietary Names
INN number INN
68 folic acid
Synonyms
folate
Database Links
CAS Registry No. 59-30-3 (source: Scifinder)
ChEBI CHEBI:27470
DrugBank Ligand DB00158
Human Metabolome Database HMDB00121
Search on ChemSpider OVBPIULPVIDEAO-LBPRGKRZSA-N
Wikipedia Folic_acid

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org