Ligand Id: 4675
Ligand name tetrahydrofolic acid

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 9
Rotatable bonds 10
Topological polar surface area 206.94
Molecular weight 446.18
XLogP -3.04
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: DrugBank)
DrugBank groups approved; nutraceutical
IUPAC Name
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Synonyms
tetrahydrofolate
Database Links
DrugBank Ligand DB00116
Search on ChemSpider MSTNYGQPCMXVAQ-KIYNQFGBSA-N
ZINC ZINC13513942, ZINC13513943

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org