S(+)-niguldipine

Ligand id: 487

Name: S(+)-niguldipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 111.01
Molecular weight 609.28
XLogP 11.91
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
O3-[3-[4,4-di(phenyl)piperidin-1-yl]propyl] O5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
6106 niguldipine
Synonyms
(+)-niguldipine
Database Links
BindingDB Ligand 50034683
CAS Registry No. 113165-32-5 (source: Scifinder)
ChEMBL Ligand CHEMBL405355
PubChem CID 60602
Search Google for chemical match using the InChIKey SVJMLYUFVDMUHP-XIFFEERXSA-N
Search Google for chemicals with the same backbone SVJMLYUFVDMUHP
Search PubMed clinical trials niguldipine
Search PubMed titles niguldipine
Search PubMed titles/abstracts niguldipine
Search UniChem for chemical match using the InChIKey SVJMLYUFVDMUHP-XIFFEERXSA-N
Search UniChem for chemicals with the same backbone SVJMLYUFVDMUHP
Comments
The following stereoisomers and enantiomers of niguldipine exist: R(-)-niguldipine (dexniguldipine, INN), and S(+)-niguldipine.