PQ401

Ligand id: 5048

Name: PQ401

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 63.25
Molecular weight 341.09
XLogP 4.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(5-chloro-2-methoxyphenyl)-1-(2-methylquinolin-4-yl)urea
Synonyms
IGF-1R inhibitor II | PQ 401 | PQ-401
Database Links
CAS Registry No. 196868-63-0 (source: Scifinder)
ChEMBL Ligand CHEMBL439259
PubChem CID 9549305
Search Google for chemical match using the InChIKey YBLWOZUPHDKFOT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YBLWOZUPHDKFOT
Search UniChem for chemical match using the InChIKey YBLWOZUPHDKFOT-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YBLWOZUPHDKFOT
Comments
PQ401 inhibits phosphorylation of the insulin-like growth factor 1 receptor (IGF1R) kinase domain [2].