JNJ1661010

Ligand id: 5206

Name: JNJ1661010

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 89.6
Molecular weight 365.13
XLogP 4.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide
Synonyms
JNJ 1661010 | JNJ-1661010
Database Links
CAS Registry No. 681136-29-8
ChEMBL Ligand CHEMBL460273
PubChem CID 2809273
Search Google for chemical match using the InChIKey BHBOSTKQCZEAJM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BHBOSTKQCZEAJM
Search UniChem for chemical match using the InChIKey BHBOSTKQCZEAJM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BHBOSTKQCZEAJM
Comments
JNJ1661010 is an inhibitor of fatty acid amide hydrolase (FAAH). The apparent IC50 is time-dependent, and binding is slowly reversible due to the formation of a covalent intermediate which is hydrolysed to release the compound [1].