STO609

Ligand id: 5274

Name: STO609

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 57.61
Molecular weight 314.07
XLogP 4.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
11-oxo-3,10-diazapentacyclo[10.7.1.0^{2,10}.0^{4,9}.0^{16,20}]icosa-1(19),2,4,6,8,12,14,16(20),17-nonaene-17-carboxylic acid
Synonyms
STO 609 | STO-609
Database Links
CAS Registry No. 52029-86-4
ChEMBL Ligand CHEMBL1182777
PubChem CID 3467590
RCSB PDB Ligand 609
Search Google for chemical match using the InChIKey MYKOWOGZBMOVBJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MYKOWOGZBMOVBJ
Search UniChem for chemical match using the InChIKey MYKOWOGZBMOVBJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MYKOWOGZBMOVBJ
Comments
STO609 is a selective and cell-permeable inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinases CaMKK1 and CaMKK2 [3]. The compound has been assessed in preclinical studies.