GSK-1838705A

Ligand id: 5683

Name: GSK-1838705A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 10
Topological polar surface area 127.51
Molecular weight 532.23
XLogP 2.51
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydro-1H-indol-6-yl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-6-fluoro-N-methylbenzamide
Synonyms
GSK 1838705A | GSK1838705A
Database Links
CAS Registry No. 1186659-59-5
ChEMBL Ligand CHEMBL464552
PubChem CID 25182616
Search Google for chemical match using the InChIKey HZTYDQRUAWIZRE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HZTYDQRUAWIZRE
Search UniChem for chemical match using the InChIKey HZTYDQRUAWIZRE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HZTYDQRUAWIZRE
Comments
GSK-1838705A is an experimental inhibitor of the insulin receptor (INSR), insulin-like growth factor I receptor (IGF1R), and anaplastic lymphoma receptor tyrosine kinase (ALK) [2], with little inhibitory effect on other kinases.