GSK-461364A

Ligand id: 5684

Name: GSK-461364A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 104.86
Molecular weight 543.19
XLogP 5.11
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-{6-[(4-methylpiperazin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
Synonyms
GSK 461364 | GSK-461364 | GSK461364 | GSK461364A
Database Links
CAS Registry No. 929095-18-1
ChEMBL Ligand CHEMBL1908394
PubChem CID 15983966
Search Google for chemical match using the InChIKey ZHJGWYRLJUCMRT-QGZVFWFLSA-N
Search Google for chemicals with the same backbone ZHJGWYRLJUCMRT
Search UniChem for chemical match using the InChIKey ZHJGWYRLJUCMRT-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone ZHJGWYRLJUCMRT
Comments
GSK-461364A is an inhibitor of polo-like kinase 1 (PLK1) [2].