tandutinib

Ligand id: 5695

Name: tandutinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 79.4
Molecular weight 561.33
XLogP 4.45
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide
International Nonproprietary Names
INN number INN
8501 tandutinib
Synonyms
CT53518 | MLN-518 | MLN518
Database Links
CAS Registry No. 387867-13-2
PubChem CID 66524380
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Search UniChem for chemical match using the InChIKey SGVQMZVRLBDVCF-UHFFFAOYSA-N
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Comments
Tandutinib is reported as a fms-related tyrosine kinase 3 (FLT3) inhibitor, although it has almost identical IC50s for PDGRFβ and KIT [4].