vatalanib

Ligand id: 5705

Name: vatalanib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 50.7
Molecular weight 346.1
XLogP 5.99
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
International Nonproprietary Names
INN number INN
7994 vatalanib
Synonyms
CGP 79787 | CGP-7978 | PTK787 | pynasunate | ZK-232934 | ZK222584
Database Links
CAS Registry No. 212141-54-3
ChEMBL Ligand CHEMBL101253
DrugBank Ligand DB04879
PubChem CID 151194
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Wikipedia Vatalanib
Comments
Vatalanib is a potent and orally biovailable inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases [8].