IL-1 receptor antagonist

Ligand id: 5878

Name: IL-1 receptor antagonist

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
IL1RN interleukin 1 receptor antagonist Human prepro-interleukin-1 receptor antagonist protein ICIL-1RA, IL1F3, IL1RA, IL-1RN, interleukin-1 receptor antagonist protein, intracellular interleukin-1 receptor antagonist, IRAP, MGC10430
Synonyms
IL-1ra | interleukin-1 receptor antagonist protein | IRAP
Database Links
Ensembl Gene ENSG00000136689 (Hs)
Human Protein Atlas ENSG00000136689 (Hs)
SynPHARM 77163 (in complex with Interleukin-1 receptor, type I)
UniProtKB P18510 (Hs)
Wikipedia IL1RN
Comments
A recombinant, non-glycosylated version of this protein is marketed as rheumatoid arthritis drug Anakinra.