Rho kinase inhibitor IV

Ligand id: 6033

Name: Rho kinase inhibitor IV

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	4
Topological polar surface area	104.98
Molecular weight	376.16
XLogP	0.4
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepan-1-yl]ethan-1-one

IUPAC Name

2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepan-1-yl]ethan-1-one

Synonyms
glycyl-H 1152

Synonyms

glycyl-H 1152

Comments
This is compound 18 in [3]. It is a selective and potent Rho kinase inhibitor

Comments

This is compound 18 in [3]. It is a selective and potent Rho kinase inhibitor

Database Links
CAS Registry No.	913844-46-9
GtoPdb PubChem SID	178102655
PubChem CID	11976582
Search Google for chemical match using the InChIKey	CMKMGFAUKPAOMG-AWEZNQCLSA-N
Search Google for chemicals with the same backbone	CMKMGFAUKPAOMG
Search UniChem for chemical match using the InChIKey	CMKMGFAUKPAOMG-AWEZNQCLSA-N
Search UniChem for chemicals with the same backbone	CMKMGFAUKPAOMG