tivozanib

Ligand id: 6058

Name: tivozanib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 107.74
Molecular weight 454.1
XLogP 3.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea
International Nonproprietary Names
INN number INN
9203 tivozanib
Synonyms
AV-951 | KRN-951 | VEGFR tyrosine kinase inhibitor IV
Database Links
CAS Registry No. 475108-18-0
ChEMBL Ligand CHEMBL1289494
PubChem CID 9911830
RCSB PDB Ligand AV9
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Search UniChem for chemical match using the InChIKey SPMVMDHWKHCIDT-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SPMVMDHWKHCIDT
SynPHARM 79680 (in complex with kinase insert domain receptor)
Wikipedia Tivozanib