methocarbamol

Ligand id: 6829

Name: methocarbamol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 91.01
Molecular weight 241.1
XLogP 0.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name
2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
International Nonproprietary Names
INN number INN
776 methocarbamol
Synonyms
Robaxin®
Database Links
CAS Registry No. 532-03-6
ChEMBL Ligand CHEMBL1201117
DrugBank Ligand DB00423
PubChem CID 4107
Search Google for chemical match using the InChIKey GNXFOGHNGIVQEH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GNXFOGHNGIVQEH
Search PubMed clinical trials methocarbamol
Search PubMed titles methocarbamol
Search PubMed titles/abstracts methocarbamol
Search UniChem for chemical match using the InChIKey GNXFOGHNGIVQEH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GNXFOGHNGIVQEH
Wikipedia Methocarbamol
Comments
Methocarbamol is the carbamate of guaifenesin, but the carbamate bond is not metabolically hydrolysed, so guaifenesin is not a metabolite of methocarbamol. Methocarbamol has reduced abuse potential compared to other carbamate drugs such as meprobamate and its prodrug carisoprodol.