RVX 208

Ligand id: 7034

Name: RVX 208

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 89.05
Molecular weight 371.16
XLogP 1.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-1,4-dihydroquinazolin-4-one
Synonyms
QC-216 | RVX-000222 | RVX-208
Database Links
CAS Registry No. 1044870-39-4
ChEMBL Ligand CHEMBL2393130
PubChem CID 24871506
RCSB PDB Ligand 1K0
Search Google for chemical match using the InChIKey NETXMUIMUZJUTB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NETXMUIMUZJUTB
Search UniChem for chemical match using the InChIKey NETXMUIMUZJUTB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NETXMUIMUZJUTB
SynPHARM 82687 (in complex with bromodomain containing 2)
82686 (in complex with bromodomain containing 4)
Wikipedia RVX_208
Comments
RVX 208 is a derivative of the plant polyphenol resveratrol. RVX 208 is an investigational antagonist of BET bromodomain containing proteins, with potential anti-atherosclerotic action for the treatment of cardiovascular disease (CVD) [2-3].