loteprednol etabonate

Ligand id: 7085

Name: loteprednol etabonate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 99.13
Molecular weight 466.18
XLogP 3.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1998))
IUPAC Name
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
International Nonproprietary Names
INN number INN
6654 loteprednol
Synonyms
HGP-1
Lotemax®
P-5604
Database Links
CAS Registry No. 82034-46-6
ChEMBL Ligand CHEMBL1200865
DrugBank Ligand DB00873
PubChem CID 444025
Search Google for chemical match using the InChIKey DMKSVUSAATWOCU-HROMYWEYSA-N
Search Google for chemicals with the same backbone DMKSVUSAATWOCU
Search PubMed clinical trials loteprednol
Search PubMed titles loteprednol
Search PubMed titles/abstracts loteprednol
Wikipedia Loteprednol
Comments
Loteprednol is a corticosteroid.