Synonyms: O-desmethylvenlafaxine (ODV) | Pristiq® | WY-45233
desvenlafaxine is an approved drug (FDA (2008))
Compound class:
Synthetic organic
Comment: Desvenlafaxine belongs to the group of serotonin–norepinephrine reuptake inhibitors (SNRIs) which are antidepressants. Desvenlafaxine is the major active metabolite of venlafaxine.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖View more information in the IUPHAR Pharmacology Education Project: desvenlafaxine |
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No information available. |
Summary of Clinical Use |
Used to treat major depressive disorder. |
Mechanism Of Action and Pharmacodynamic Effects |
By inhibiting the re-uptake of serotonin and norepinephrine in the CNS, this drug potentiates their activity and this improves mood. |
External links |
For extended ADME data see the following: Drugs.com |