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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide |
Comments |
SRT1720 is a selective SIRT1 activator. SRT1720 binds to the SIRT1 enzyme–peptide substrate complex at an allosteric site amino-terminal to the catalytic domain [2]. In vivo studies show that SIRT1 activation has the potential to improve insulin sensitivity in animal models of obesity, and improve glucose homeostasis [2]. This indicates the potential of such compounds as treatment for type II diabetes. |
Database Links ![]() |
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CAS Registry No. | 925434-55-5 |
ChEMBL Ligand | CHEMBL257991 |
GtoPdb PubChem SID | 223366036 |
PubChem CID | 24180125 |
RCSB PDB Ligand | SR7 |
Search Google for chemical match using the InChIKey | IASPBORHOMBZMY-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | IASPBORHOMBZMY |
Search UniChem for chemical match using the InChIKey | IASPBORHOMBZMY-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | IASPBORHOMBZMY |
Wikipedia | SRT1720 |