baricitinib

Ligand id: 7792

Name: baricitinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 128.94
Molecular weight 371.12
XLogP -0.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA & FDA (2017))
IUPAC Name
2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
International Nonproprietary Names
INN number INN
9570 baricitinib
Synonyms
INCB-028050 | LY-3009104 | LY3009104 | Olumiant®
Database Links
CAS Registry No. 1187594-09-7
ChEMBL Ligand CHEMBL2105759
GtoPdb PubChem SID 223366123
PubChem CID 44205240
RCSB PDB Ligand 3JW
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Wikipedia Baricitinib
Comments
Baricitinib is a JAK1 and 2 selective inhibitor. The compound is orally bioavailable.