galunisertib

Ligand id: 7797

Name: galunisertib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 86.69
Molecular weight 369.16
XLogP 3.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline-6-carboxamide
International Nonproprietary Names
INN number INN
9768 galunisertib
Synonyms
LY-2157299 | LY2157299
Database Links
CAS Registry No. 700874-72-2
ChEMBL Ligand CHEMBL2364611
PubChem CID 10090485
Search Google for chemical match using the InChIKey IVRXNBXKWIJUQB-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey IVRXNBXKWIJUQB-UHFFFAOYSA-N
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Comments
Galunisertib is an investigational inhibitor of the receptor tyrosine kinase, TGFβR.