OTS964

Ligand id: 7813

Name: OTS964

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 80.81
Molecular weight 392.16
XLogP 4.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
9-{4-[(2R)-1-(dimethylamino)propan-2-yl]phenyl}-8-hydroxy-6-methyl-4H,5H-thieno[2,3-c]quinolin-4-one
Database Links
PubChem CID 67448186
Search Google for chemical match using the InChIKey XCFRUAOZMVFDPQ-AWEZNQCLSA-N
Search Google for chemicals with the same backbone XCFRUAOZMVFDPQ
Search UniChem for chemical match using the InChIKey XCFRUAOZMVFDPQ-AWEZNQCLSA-N
Search UniChem for chemicals with the same backbone XCFRUAOZMVFDPQ
Comments
OTS964 is a potent and selective inhibitor of the PDZ binding kinase, PBK (aka TOPK) [2]. The compound is undergoing pre-clinical assessment.