TCN-201

Ligand id: 7846

Name: TCN-201

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 112.75
Molecular weight 461.06
XLogP 5.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[[4-[(benzoylamino)carbamoyl]phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide
Synonyms
QCR-22
Database Links
CAS Registry No. 852918-02-6
ChEMBL Ligand CHEMBL2333945
PubChem CID 4787937
RCSB PDB Ligand 67P
Search Google for chemical match using the InChIKey FYIBXBFDXNPBSF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FYIBXBFDXNPBSF
Search UniChem for chemical match using the InChIKey FYIBXBFDXNPBSF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FYIBXBFDXNPBSF
Comments
TCN-201 is compound 1 in [1]. TCN-201 is a potent negative allosteric modulator of glycine but not glutamate at GluN2A NMDA receptors [2].