ridaforolimus

Ligand id: 7884

Name: ridaforolimus

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 15
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 211.31
Molecular weight 989.56
XLogP 5.08
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
8822 ridaforolimus
Synonyms
AP-23573 | AP23573 | deforolimus | MK-8669
Database Links
ChEMBL Ligand CHEMBL2103839
PubChem CID 11520894
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Wikipedia Ridaforolimus
Comments
Ridaforolimus is an investigational targeted and small-molecule inhibitor of the protein kinase mTOR [2]. mTOR inhibition is hypothesised to provide maintenance therapy for patients with metastatic soft-tissue and bone sarcoma who generally have a poor prognosis despite receiving chemotherapy [1].