filgotinib

Ligand id: 7913

Name: filgotinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 105.05
Molecular weight 425.15
XLogP 2.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
International Nonproprietary Names
INN number INN
9720 filgotinib
Synonyms
GLPG-0634 | GLPG0634
Database Links
CAS Registry No. 1206161-97-8
ChEMBL Ligand CHEMBL3301607
PubChem CID 49831257
RCSB PDB Ligand 2HB
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SynPHARM 80797 (in complex with Janus kinase 2)
Wikipedia Filgotinib
Comments
Filgotinib is a selective JAK1 inhibitor [1].