PD 0325901

Ligand id: 7935

Name: PD 0325901

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 8
Topological polar surface area 90.82
Molecular weight 482
XLogP 3.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Synonyms
PD-0325901 | PD0325901
Database Links
CAS Registry No. 391210-10-9
ChEMBL Ligand CHEMBL507361
PubChem CID 9826528
RCSB PDB Ligand 4BM
Search Google for chemical match using the InChIKey SUDAHWBOROXANE-SECBINFHSA-N
Search Google for chemicals with the same backbone SUDAHWBOROXANE
Search UniChem for chemical match using the InChIKey SUDAHWBOROXANE-SECBINFHSA-N
Search UniChem for chemicals with the same backbone SUDAHWBOROXANE
SynPHARM 80833 (in complex with mitogen-activated protein kinase kinase 1)
Comments
PD 0325901 is a selective and non ATP-competitive MEK inhibitor [1].