tivantinib

Ligand id: 7948

Name: tivantinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 66.89
Molecular weight 369.15
XLogP 3.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
9326 tivantinib
Synonyms
ARQ-197 | ARQ197
Database Links
CAS Registry No. 905854-02-6,
ChEMBL Ligand CHEMBL2103882
PubChem CID 11494412
RCSB PDB Ligand TIV
Search Google for chemical match using the InChIKey UCEQXRCJXIVODC-PMACEKPBSA-N
Search Google for chemicals with the same backbone UCEQXRCJXIVODC
Search PubMed clinical trials tivantinib
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Search PubMed titles/abstracts tivantinib
Search UniChem for chemical match using the InChIKey UCEQXRCJXIVODC-PMACEKPBSA-N
Search UniChem for chemicals with the same backbone UCEQXRCJXIVODC
Wikipedia Tivantinib
Comments
Tivantinib is an allosteric inhibitor of c-MET kinase (hepatocyte growth factor receptor), with antineoplastic potential [5].