ralimetinib

Ligand id: 7959

Name: ralimetinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 85.41
Molecular weight 420.24
XLogP 5.69
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-[2-tert-butyl-5-(4-fluorophenyl)-3H-imidazol-4-yl]-3-(2,2-dimethylpropyl)imidazo[5,4-b]pyridin-2-amine
International Nonproprietary Names
INN number INN
9753 ralimetinib
Synonyms
LY-2228820 | LY-2228820 free base | LY2228820
Database Links
CAS Registry No. 862505-00-8
ChEMBL Ligand CHEMBL2364626
PubChem CID 11539025
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Comments
Ralimetinib is a potent and selective, ATP-competitive inhibitor of p38 MAPK α and β [1]. The compound is delivered orally as the dimesylate salt (PubChem CID 11570805). It is compound 40 in Mader et al. (2008) [2].