pilaralisib

Ligand id: 7963

Name: pilaralisib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 146.38
Molecular weight 448.08
XLogP 5.1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[3-(2,1,3-benzothiadiazol-6-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
International Nonproprietary Names
INN number INN
9708 pilaralisib
Synonyms
SAR-245408 | XL-147 | XL147
Database Links
CAS Registry No. 956958-53-5 (source: Scifinder)
ChEBI CHEBI:71957
ChEMBL Ligand CHEMBL3218575
PubChem CID 1893730
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Comments
Pilaralisib is an orally bioavailable small molecule inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases, with potential antineoplastic activity [1-2].