SB-415286

Ligand id: 8019

Name: SB-415286

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 121.57
Molecular weight 359.03
XLogP 3.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)pyrrole-2,5-dione
Synonyms
SB 415286 | SB415286
Database Links
CAS Registry No. 264218-23-7
ChEMBL Ligand CHEMBL322970
PubChem CID 4210951
Search Google for chemical match using the InChIKey PQCXVIPXISBFPN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PQCXVIPXISBFPN
Search UniChem for chemical match using the InChIKey PQCXVIPXISBFPN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PQCXVIPXISBFPN
Comments
SB-415286 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor which is equipotent at the α and β isozymes [2].