GSK-LSD1

Ligand id: 8241

Name: GSK-LSD1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 24.06
Molecular weight 216.16
XLogP 3.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine
Comments
GSK-LSD1 is a potent, selective and irreversible inhibitor of lysine specific demethylase 1 (LSD1; gene symbol KDM1A) [1]. The compound was developed by GlaxoSmithKline and has been made available for inclusion in the portfolio of compounds held by the Structural Genomics Consortium (SGC) in their Epigenetics Probes Collection.
Database Links
GtoPdb PubChem SID 249565921
PubChem CID 71522234
Search Google for chemical match using the InChIKey BASFYRLYJAZPPL-UONOGXRCSA-N
Search Google for chemicals with the same backbone BASFYRLYJAZPPL
Search UniChem for chemical match using the InChIKey BASFYRLYJAZPPL-UONOGXRCSA-N
Search UniChem for chemicals with the same backbone BASFYRLYJAZPPL