GSK-LSD1

Ligand id: 8241

Name: GSK-LSD1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 24.06
Molecular weight 216.16
XLogP 3.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine
Database Links
PubChem CID 71522234
Search Google for chemical match using the InChIKey BASFYRLYJAZPPL-UONOGXRCSA-N
Search Google for chemicals with the same backbone BASFYRLYJAZPPL
Search UniChem for chemical match using the InChIKey BASFYRLYJAZPPL-UONOGXRCSA-N
Search UniChem for chemicals with the same backbone BASFYRLYJAZPPL
Comments
GSK-LSD1 is a potent, selective and irreversible inhibitor of lysine specific demethylase 1 (LSD1; gene symbol KDM1A) [1]. The compound was developed by GlaxoSmithKline and has been made available for inclusion in the portfolio of compounds held by the Structural Genomics Consortium (SGC) in their Epigenetics Probes Collection.