SD-208

Ligand id: 8246

Name: SD-208

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 76.48
Molecular weight 352.06
XLogP 3.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine
Synonyms
SCI-208 [2] | SD 208
Database Links
CAS Registry No. 627536-09-8
ChEMBL Ligand CHEMBL238125
PubChem CID 10316032
Search Google for chemical match using the InChIKey BERLXWPRSBJFHO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BERLXWPRSBJFHO
Search UniChem for chemical match using the InChIKey BERLXWPRSBJFHO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BERLXWPRSBJFHO
Comments
SD-208 is a selective, ATP-competitive inhibitor of TGFβR1 (ALK5) [2]. SD-208 is compound 14 in patent WO2005032481 [1].