LY2584702

Ligand id: 8248

Name: LY2584702

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 75.52
Molecular weight 445.16
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methylimidazol-2-yl]piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
Synonyms
LY 2584702 | LY-2584702
Database Links
CAS Registry No. 1082949-67-4
PubChem CID 25118925
Search Google for chemical match using the InChIKey FYXRSVDHGLUMHB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FYXRSVDHGLUMHB
Search UniChem for chemical match using the InChIKey FYXRSVDHGLUMHB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FYXRSVDHGLUMHB
Comments
LY2584702 is reported as an ATP competitive, selective inhibitor of the p70 ribosomal protein S6 kinase (p70S6K) [2]. p70S6K is a downstream component of the PI3K/Akt/mTOR signalling pathway regulating cell proliferation and survival.