osilodrostat

Ligand id: 8310

Name: osilodrostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 41.61
Molecular weight 227.09
XLogP 2.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
International Nonproprietary Names
INN number INN
9818 osilodrostat
Synonyms
LCI-699 | LCI699
Database Links
CAS Registry No. 928134-65-0
ChEMBL Ligand CHEMBL3099695
PubChem CID 44139752
Search Google for chemical match using the InChIKey USUZGMWDZDXMDG-CYBMUJFWSA-N
Search Google for chemicals with the same backbone USUZGMWDZDXMDG
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Search UniChem for chemical match using the InChIKey USUZGMWDZDXMDG-CYBMUJFWSA-N
Search UniChem for chemicals with the same backbone USUZGMWDZDXMDG
Comments
Osilodrostat was designed as an inhibitor of aldosterone synthase (CYP11B2), but is also reported to inhibit the closely related enzyme, 11-beta-hydroxylase (CYP11B1) [7].