osilodrostat

Ligand id: 8310

Name: osilodrostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 41.61
Molecular weight 227.09
XLogP 2.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
International Nonproprietary Names
INN number INN
9818 osilodrostat
Synonyms
LCI-699 | LCI699
Comments
Osilodrostat was designed as an inhibitor of aldosterone synthase (CYP11B2), but is also reported to inhibit the closely related enzyme, 11-beta-hydroxylase (CYP11B1) [7].
Database Links
CAS Registry No. 928134-65-0
ChEMBL Ligand CHEMBL3099695
GtoPdb PubChem SID 252166522
PubChem CID 44139752
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