talazoparib

Ligand id: 8313

Name: talazoparib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 84.2
Molecular weight 380.12
XLogP 3.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
9868 talazoparib
Synonyms
BMN-673
Database Links
ChEMBL Ligand CHEMBL3137320
PubChem CID 44819241
Search Google for chemical match using the InChIKey IUEWAGVJRJORLA-HZPDHXFCSA-N
Search Google for chemicals with the same backbone IUEWAGVJRJORLA
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Search UniChem for chemical match using the InChIKey IUEWAGVJRJORLA-HZPDHXFCSA-N
Search UniChem for chemicals with the same backbone IUEWAGVJRJORLA
SynPHARM 81953 (in complex with poly(ADP-ribose) polymerase 1)
81954 (in complex with poly(ADP-ribose) polymerase 2)
Comments
Talazoparib is a PARP inhibitor [5], inhibiting both PARP1 and PARP2 [1,5]. The compound may be used experimentally as a tosylate salt (PubChem CID 56966514).