tacedinaline

Ligand id: 8367

Name: tacedinaline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 84.22
Molecular weight 269.12
XLogP 2.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-acetamido-N-(2-aminophenyl)benzamide
International Nonproprietary Names
INN number INN
8328 tacedinaline
Synonyms
CI994
Database Links
CAS Registry No. 112522-64-2 (source: Scifinder)
ChEMBL Ligand CHEMBL235191
PubChem CID 2746
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Comments
Tacedinaline inhibits the histone deacetylase enzyme HDAC1 [6], and is reported to have antitumour activity in preclinical studies [2,4-5].