navarixin

Ligand id: 8497

Name: navarixin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 111.88
Molecular weight 397.16
XLogP 3.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxo-1-cyclobutenyl]amino]benzamide
International Nonproprietary Names
INN number INN
9464 navarixin
Synonyms
SCH-527123 | SCH527123
Database Links
CAS Registry No. 473727-83-2
ChEMBL Ligand CHEMBL216981
PubChem CID 9865554
Search Google for chemical match using the InChIKey RXIUEIPPLAFSDF-CYBMUJFWSA-N
Search Google for chemicals with the same backbone RXIUEIPPLAFSDF
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Search UniChem for chemical match using the InChIKey RXIUEIPPLAFSDF-CYBMUJFWSA-N
Search UniChem for chemicals with the same backbone RXIUEIPPLAFSDF
Comments
Navarixin (SCH-527123) is a potent and orally bioavailable CXCR2/CXCR1 receptor antagonist [2].