GW853606

Ligand id: 8645

Name: GW853606

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 98.38
Molecular weight 494.99
XLogP 5.69
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(2-bromophenyl)methoxy]-5-[6-(trifluoromethyl)benzimidazol-1-yl]thiophene-2-carboxamide
Synonyms
compound 22 [PMID: 19097784] | GW853606X
Database Links
ChEMBL Ligand CHEMBL481510
PubChem CID 25263088
Search Google for chemical match using the InChIKey LOKKVFGDJAVMLU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LOKKVFGDJAVMLU
Search UniChem for chemical match using the InChIKey LOKKVFGDJAVMLU-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LOKKVFGDJAVMLU
Comments
GW853606 is an inhibitor of the polo-like kinase, PLK1 [1].