finerenone

Ligand id: 8678

Name: finerenone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 110.26
Molecular weight 378.17
XLogP 1.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
Synonyms
BAY 94-8862
Database Links
PubChem CID 60150535
Search Google for chemical match using the InChIKey BTBHLEZXCOBLCY-QGZVFWFLSA-N
Search Google for chemicals with the same backbone BTBHLEZXCOBLCY
Search UniChem for chemical match using the InChIKey BTBHLEZXCOBLCY-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone BTBHLEZXCOBLCY
Comments
Finerenone (BAY 94-8862) is a next generation oral, non-steroidal Mineralocorticoid Receptor antagonist which blocks the deleterious effects of aldosterone. Finerenone is currently in clinical Phase IIb development for the treatment of worsening chronic heart failure [2], as well as diabetic nephropathy.