INCB3619

Ligand id: 8679

Name: INCB3619

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 99.18
Molecular weight 413.2
XLogP 2.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
methyl (5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl3,6-dihydro-2H-pyridine-1-carbonyl)-7-azaspiro[2.5]octane-7-carboxylate
Synonyms
compound 52 [1] | INCB-3619
Database Links
ChEMBL Ligand CHEMBL434567
PubChem CID 11625778
Search Google for chemical match using the InChIKey CKZHFOKQZRZCPF-ROUUACIJSA-N
Search Google for chemicals with the same backbone CKZHFOKQZRZCPF
Search UniChem for chemical match using the InChIKey CKZHFOKQZRZCPF-ROUUACIJSA-N
Search UniChem for chemicals with the same backbone CKZHFOKQZRZCPF
Comments
INCB3619 was developed as an ADAM10 inhibitor, but also markedly inhibits ADAM17, MMP12 and MMP15 [1].