RP5264

Ligand id: 8916

Name: RP5264

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 105.15
Molecular weight 571.18
XLogP 6.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one
Synonyms
example A1 [US2014011819] | RP-5264 | TGR-1202
Database Links
CAS Registry No. 1532533-67-7 (source: PubChem)
PubChem CID 72950888
Search Google for chemical match using the InChIKey IUVCFHHAEHNCFT-INIZCTEOSA-N
Search Google for chemicals with the same backbone IUVCFHHAEHNCFT
Search UniChem for chemical match using the InChIKey IUVCFHHAEHNCFT-INIZCTEOSA-N
Search UniChem for chemicals with the same backbone IUVCFHHAEHNCFT
Comments
RP5264 is an orally available, selective inhibitor of the δ isoform of phosphoinositide 3-kinase (PI3K) [1].