ADL5747

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Ligands
ADL5747

Ligand id: 9003

Name: ADL5747

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	5
Topological polar surface area	61.8
Molecular weight	392.21
XLogP	3.73
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
N,N-diethyl-3-hydroxy-4-spiro[chromene-2,4'-piperidine]-4-ylbenzamide

IUPAC Name

N,N-diethyl-3-hydroxy-4-spiro[chromene-2,4'-piperidine]-4-ylbenzamide

Synonyms
ADL 5747 \| ADL-5747 \| compound 36 [PMID: 19694468]

Synonyms

ADL 5747 | ADL-5747 | compound 36 [PMID: 19694468]

Database Links
BindingDB Ligand	50297342
CAS Registry No.	850176-30-6
ChEMBL Ligand	CHEMBL561339
GtoPdb PubChem SID	310264781
PubChem CID	11200189
Search Google for chemical match using the InChIKey	ALGHKWSXJUQNJJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	ALGHKWSXJUQNJJ
Search UniChem for chemical match using the InChIKey	ALGHKWSXJUQNJJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	ALGHKWSXJUQNJJ

Comments
ADL5747 is a selective, nonpeptidic δ opioid receptor agonist [1]. Due to its favorable efficacy, safety, and pharmacokinetic profile ADL5747 was progressed as a clinical candidate for the treatment of pain.

Comments

ADL5747 is a selective, nonpeptidic δ opioid receptor agonist [1]. Due to its favorable efficacy, safety, and pharmacokinetic profile ADL5747 was progressed as a clinical candidate for the treatment of pain.